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Hello Everyone,</div>
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<div class="ContentPasted0">The next CTN Seminar will take place one week from today:
<b>Tuesday, March 21 at 3:30 p.m. in E5-2004</b>. Our speaker is <a href="https://sites.google.com/site/mauriziodepitta/" title="https://sites.google.com/site/mauriziodepitta/" data-loopstyle="link">Maurizio de Pitta</a> from the Krembil Research Institute.
Title and abstract are below.</div>
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<div class="ContentPasted0"><b>Please note this an in-person seminar!</b></div>
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<div class="ContentPasted0">Prof. de Pitta will be visiting for the day. If you are interested in meeting with him, please contact me (sacampbell@uwaterloo.ca).</div>
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<div class="ContentPasted0">Graduate students who are interested in joining Prof. de Pitta for lunch, please contact me (sacampbell@uwaterloo.ca) by Friday, March 17 at 4 p.m.</div>
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<div class="ContentPasted0">Regards,</div>
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<div class="ContentPasted0">Sue Ann</div>
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<b>Title: </b>Neuron-glial switches
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<div class="ContentPasted1"><b>Abstract:</b></div>
<div class="ContentPasted1">Healthy brain functions rely on the intricate interaction of neurons with glial cells. Among the latter, astrocytes are ubiquitous in our cortical circuits and can affect synaptic transmission on multiple time scales. On the short
time scale, they are responsible, for example, for glutamate clearance, which is critical in setting the tone of neural activity. On a longer time scale, astrocytes operate as endocrine cells, modulating synaptic function by releasing common transmitter molecules.
Although different in nature, both pathways may mediate positive feedback on neural activity, resulting in the emergence of multistability. In this scenario, the multiple activity states emerging from neuron-astrocyte interactions could account for various
cognitive-related mechanisms in the healthy and diseased brain: from working-memory tasks to dementia-related neural correlates.</div>
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<p style="margin-top:0px; margin-bottom:0px">_______________________________________________</p>
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<p style="margin-top:0px; margin-bottom:0px">Dr. Sue Ann Campbell (she/her)</p>
<p style="margin-top:0px; margin-bottom:0px">Professor and University Research Chair</p>
<p style="margin-top:0px; margin-bottom:0px">Department of Applied Mathematics, University of Waterloo</p>
<p style="margin-top:0px; margin-bottom:0px">Waterloo ON N2L 3G1</p>
<p style="margin-top:0px; margin-bottom:0px"><a href="https://www.math.uwaterloo.ca/~sacampbe/" class="OWAAutoLink">https://www.math.uwaterloo.ca/~sacampbe/</a></p>
<p style="margin-top:0px; margin-bottom:0px">President-Elect, <a href="https://caims.ca/" title="https://caims.ca/" style="font-family:Calibri,Helvetica,sans-serif; font-size:12pt" data-loopstyle="link">Canadian Applied and Industrial Mathematics Society</a></p>
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<p style="margin-top:0px; margin-bottom:0px"><i>I acknowledge that I live and work on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. The University of Waterloo main campus is located on the Haldimand tract, the land granted
to the Six Nations that includes six miles on each side of the Grand River.</i></p>
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