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</o:shapelayout></xml><![endif]--></head><body bgcolor=white lang=EN-CA link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Hi all:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>See info wrt a webinar below.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Register if interested.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Thx.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Glen<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div><div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm'><p class=MsoNormal><b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> Prostate Cancer Canada [mailto:pccmail=prostatecancer.ca@mail91.us4.mcsv.net] <b>On Behalf Of </b>Prostate Cancer Canada<br><b>Sent:</b> January 7, 2016 11:15 AM<br><br><b>Subject:</b> Expert Angle with Dr. Ralph Buttyan: "Embryonic Re-Awakening" in Prostate Cancer<o:p></o:p></span></p></div></div><p class=MsoNormal><o:p> </o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white;border-collapse:collapse'><tr><td width="100%" valign=top style='width:100.0%;padding:15.0pt 15.0pt 15.0pt 15.0pt'><div align=center><table class=MsoNormalTable border=1 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;border-collapse:collapse;border:none'><tr><td valign=top style='border:solid #00AEEF 1.0pt;border-bottom:none;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width=366 style='width:274.5pt;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 0cm 6.75pt 13.5pt'><p class=MsoNormal style='line-height:150%'><span style='font-size:7.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:gray'>Expert Angle – Interact with prostate cancer experts <o:p></o:p></span></p></td></tr></table><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=right width=197 style='width:147.75pt;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 0cm'><p class=MsoNormal style='line-height:150%'><span style='font-size:7.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:gray'><a href="http://us2.campaign-archive2.com/?u=381dca877e43c44046caa6dd1&id=1efc74ecfb&e=b7e2b89435" target="_blank"><span style='color:#606060'>View this email in your browser</span></a><br><br><o:p></o:p></span></p></td></tr></table></td></tr></table></td></tr></table></div></td></tr><tr><td valign=top style='border-top:none;border-left:solid #00AEEF 1.0pt;border-bottom:none;border-right:solid #00AEEF 1.0pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse' id=templateHeader><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><!--[if gte vml 1]><v:shapetype id="_x0000_t75" coordsize="21600,21600" o:spt="75" o:preferrelative="t" path="m@4@5l@4@11@9@11@9@5xe" filled="f" stroked="f">
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</v:shape><![endif]--><![if !vml]><img width=175 height=176 src="https://gallery.mailchimp.com/381dca877e43c44046caa6dd1/images/7e0ef8c4-13e0-46f0-be02-64a0d9db416b.png" align=right v:shapes="_x0000_s1027"><![endif]>Register for Dr. Ralph Buttyan's Webinar: "Embryonic Re-Awakening" in Prostate Cancer; Can We Improve Treatments for Advanced Disease by Targeting Embryonic Pathways?<o:p></o:p></h2><p class=MsoNormal style='line-height:110%'><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:#505050'><br></span><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:dimgray'>On Tuesday, January 12 at 7pm EST, join Dr. Ralph Buttyan as he presents <a href="http://prostatecancer.us2.list-manage.com/track/click?u=381dca877e43c44046caa6dd1&id=e74e25a594&e=b7e2b89435" target="_blank"><span style='color:#0067B1'>"Embryonic Re-Awakening" in Prostate Cancer; Can We Improve Treatments for Advanced Disease by Targeting Embryonic Pathways?</span></a><br><br>Learn from Dr. Ralph Buttyan about:</span><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:#505050'> <o:p></o:p></span></p><ul type=disc><li class=MsoNormal style='color:#505050;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:110%;mso-list:l0 level1 lfo1'><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:dimgray'>The parts of human embryonic development that become re-activated in prostate cancers that spread or are resistant to treatment</span><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif"'><o:p></o:p></span></li><li class=MsoNormal style='color:#505050;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:110%;mso-list:l0 level1 lfo1'><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:dimgray'>How this area of research is leading to novel therapeutic approaches to better control hormone resistant prostate cancer</span><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif"'><o:p></o:p></span></li><li class=MsoNormal style='color:#505050;mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:110%;mso-list:l0 level1 lfo1'><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:dimgray'>The concept of the “prostate cancer stem cell†</span><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif"'><o:p></o:p></span></li></ul></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:0cm 13.5pt 13.5pt 13.5pt'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='background:#00AEEF;border-collapse:collapse;border-radius: 5px'><tr><td style='padding:12.0pt 12.0pt 12.0pt 12.0pt'><p class=MsoNormal align=center style='text-align:center'><span style='font-family:"Arial","sans-serif"'><a href="http://prostatecancer.us2.list-manage2.com/track/click?u=381dca877e43c44046caa6dd1&id=35e8dccf62&e=b7e2b89435" target="_blank" title="Register Now"><b><span style='color:white;text-decoration:none'>Register Now</span></b></a> <o:p></o:p></span></p></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'><p class=MsoNormal style='line-height:150%'><strong><span style='font-size:10.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#505050'>Date: </span></strong><span style='font-size:10.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#505050'><a href="http://prostatecancer.us2.list-manage2.com/track/click?u=381dca877e43c44046caa6dd1&id=1bab4dd29a&e=b7e2b89435" target="_blank"><span style='color:#0067B1'>Tuesday, January 12, 2016</span></a><br><strong><span style='font-family:"Helvetica","sans-serif"'>Time:</span></strong> </span><strong><span style='font-size:10.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#00AEEF'>7:00 PM - 8:00 PM EST </span></strong><span style='font-size:10.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#505050'><br><strong><span style='font-family:"Helvetica","sans-serif"'>Speaker: </span></strong>Dr. Ralph Buttyan<br><strong><span style='font-family:"Helvetica","sans-serif"'>Location: </span></strong>Via the internet and telephone<br></span><em><span style='font-size:9.0pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#505050'>You can test your Internet connection before your Expert Angle webinar session starts by joining a test session <a href="http://prostatecancer.us2.list-manage.com/track/click?u=381dca877e43c44046caa6dd1&id=3296322fe7&e=b7e2b89435" target="_blank"><span style='color:#0067B1'>here</span></a>.</span></em><span style='font-size:10.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#505050'> <o:p></o:p></span></p></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td style='padding:7.5pt 13.5pt 7.5pt 13.5pt'><table class=MsoNormalTable border=1 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;border:none'><tr><td style='border:none;border-top:solid #00AEEF 1.0pt;padding:0cm 0cm 0cm 0cm'></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'><h2>Speaker - Dr. Ralph Buttyan<o:p></o:p></h2><p class=MsoNormal style='line-height:150%'><span style='font-size:10.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#505050'><br></span><!--[if gte vml 1]><v:shape id="_x0000_s1028" type="#_x0000_t75" alt="" style='position:absolute;margin-left:98.8pt;margin-top:0;width:150pt;height:150pt;z-index:251660288;mso-wrap-distance-left:0;mso-wrap-distance-top:0;mso-wrap-distance-right:0;mso-wrap-distance-bottom:0;mso-position-horizontal:right;mso-position-horizontal-relative:text;mso-position-vertical-relative:line' o:allowoverlap="f">
<v:imagedata src="https://gallery.mailchimp.com/381dca877e43c44046caa6dd1/images/e0e8cfe9-56fd-4f4c-8f68-1fd37d86ea6e.jpg" />
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</v:shape><![endif]--><![if !vml]><img width=200 height=200 src="https://gallery.mailchimp.com/381dca877e43c44046caa6dd1/images/e0e8cfe9-56fd-4f4c-8f68-1fd37d86ea6e.jpg" align=right v:shapes="_x0000_s1028"><![endif]><span style='font-size:10.5pt;line-height:150%;font-family:"Arial","sans-serif";color:#505050'>Dr. Buttyan received graduate training leading to a PhD in Virology in 1980 at the University of Chicago. An avid bodybuilder at the time, he subsequently joined the Urology Department of Columbia University for Postdoctoral training on the role of androgenic steroids in prostate cancer progression and treatment. He advanced to Full Professor in Pathology and Urology at the site and was Co-Director of the Urologic Malignancies Program of the Herbert Irving Cancer Center. Dr. Buttyan moved to Vancouver in 2011 to join the Vancouver Prostate Centre and he is a Professor in Urologic Sciences at the University of British Columbia. He is also the leader of the first Prostate Cancer Canada – Movember Team Grant that brings together investigators from across Canada in an effort to find better treatments for castration resistant prostate cancer. His personal research focuses on the developmental aspects of prostate cancer that drive therapeutic resistance and novel means to overcome the hormone resistant state. </span><span style='font-size:10.5pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#505050'> <o:p></o:p></span></p></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td style='padding:7.5pt 13.5pt 7.5pt 13.5pt'><table class=MsoNormalTable border=1 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;border:none'><tr><td style='border:none;border-top:solid #00AEEF 1.0pt;padding:0cm 0cm 0cm 0cm'></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width=600 style='width:450.0pt;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'><h2><span style='font-size:10.0pt'>Please check our <a href="http://prostatecancer.us2.list-manage.com/track/click?u=381dca877e43c44046caa6dd1&id=a70c429f96&e=b7e2b89435"><span style='color:#0067B1;font-weight:normal'>website</span></a> for updates and information on upcoming Expert Angle webinars.</span><o:p></o:p></h2></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td style='padding:7.5pt 13.5pt 7.5pt 13.5pt'><table class=MsoNormalTable border=1 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;border:none'><tr><td style='border:none;border-top:solid #00AEEF 1.0pt;padding:0cm 0cm 0cm 0cm'></td></tr></table></td></tr></table></td></tr></table></div></td></tr><tr><td valign=top style='border-top:none;border-left:solid #00AEEF 1.0pt;border-bottom:none;border-right:solid #00AEEF 1.0pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse' id=templateColumns><tr><td width="50%" valign=top style='width:50.0%;padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width=293 style='width:219.75pt;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'><h3><strong><span style='font-size:13.5pt;font-family:"Helvetica","sans-serif"'>What is an Expert Angle Webinar?</span></strong><o:p></o:p></h3></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 6.75pt 6.75pt 6.75pt'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 6.75pt 0cm 6.75pt'><p class=MsoNormal><!--[if gte vml 1]><v:shape id="_x0000_s1029" type="#_x0000_t75" alt="" style='position:absolute;margin-left:0;margin-top:0;width:192.75pt;height:120pt;z-index:251661312;mso-wrap-distance-left:0;mso-wrap-distance-top:0;mso-wrap-distance-right:0;mso-wrap-distance-bottom:0;mso-position-horizontal:left;mso-position-horizontal-relative:text;mso-position-vertical-relative:line' o:allowoverlap="f">
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</v:shape><![endif]--><![if !vml]><img width=257 height=160 src="https://gallery.mailchimp.com/381dca877e43c44046caa6dd1/images/gotomeeting_screen.jpg" align=left v:shapes="_x0000_s1029"><![endif]><o:p></o:p></p></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width=293 style='width:219.75pt;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'><p class=MsoNormal style='line-height:110%'><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:#505050'>A webinar is an online tool that allows people from across Canada to have an online meeting and discuss important topics, view slide shows and interact with each other. We use a service called GoToMeeting to host these webinars.<br><br>Expert Angle is a place to exchange info and ideas through a series of webinars. You’ll have the opportunity to get important information on a wide range of topics, ask questions and communicate directly with experts in their respective fields. <o:p></o:p></span></p></td></tr></table></td></tr></table></td></tr></table></td><td width="50%" valign=top style='width:50.0%;padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width=293 style='width:219.75pt;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'><p class=MsoNormal style='line-height:110%'><span style='font-size:10.5pt;line-height:110%;font-family:"Helvetica","sans-serif";color:#505050'>*After you’ve finished registering you’ll receive an email with the details on how to participate.<br><br>*You will be required to download the GoToMeeting software, <strong><span style='font-family:"Helvetica","sans-serif"'>this may take a few minutes</span></strong>.<br><br>*You can view the webinar through your PC where you can see the presentation, hear the speaker and ask questions.<br><br>*If you don’t have access to a PC you can still participate by calling into the 1-800 number and listening to the ongoing discussion.<br><br>*Only people with access to a PC during the webinar will be able to ask questions.<br><br>*Registration doesn't guarantee a seat. Only the first 100 registrants to sign into the webinar will be able to participate. So be on time! <o:p></o:p></span></p></td></tr></table></td></tr></table></td></tr></table></td></tr></table></div></td></tr><tr><td valign=top style='border-top:none;border-left:solid #00AEEF 1.0pt;border-bottom:none;border-right:solid #00AEEF 1.0pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse' id=templateBody><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width=600 style='width:450.0pt;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td style='padding:7.5pt 13.5pt 7.5pt 13.5pt'><table class=MsoNormalTable border=1 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;border:none'><tr><td style='border:none;border-top:solid #00AEEF 1.0pt;padding:0cm 0cm 0cm 0cm'></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:6.75pt 13.5pt 6.75pt 13.5pt'><p class=MsoNormal align=center style='text-align:center;line-height:150%'><strong><span 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