<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><meta http-equiv=Content-Type content="text/html; charset=utf-8"><meta name=Generator content="Microsoft Word 12 (filtered medium)"><!--[if !mso]><style>v\:* {behavior:url(#default#VML);}
o\:* {behavior:url(#default#VML);}
w\:* {behavior:url(#default#VML);}
.shape {behavior:url(#default#VML);}
</style><![endif]--><title>healthafter50</title><style><!--
/* Font Definitions */
@font-face
{font-family:Helvetica;
panose-1:2 11 6 4 2 2 2 2 2 4;}
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:Tahoma;
panose-1:2 11 6 4 3 5 4 4 2 4;}
@font-face
{font-family:Verdana;
panose-1:2 11 6 4 3 5 4 4 2 4;}
@font-face
{font-family:Georgia;
panose-1:2 4 5 2 5 4 5 2 3 3;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
margin-bottom:.0001pt;
font-size:12.0pt;
font-family:"Times New Roman","serif";}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#6E7176;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:#6E7176;
text-decoration:underline;}
p.readmsgbody, li.readmsgbody, div.readmsgbody
{mso-style-name:readmsgbody;
mso-margin-top-alt:auto;
margin-right:0cm;
mso-margin-bottom-alt:auto;
margin-left:0cm;
font-size:12.0pt;
font-family:"Times New Roman","serif";}
p.externalclass, li.externalclass, div.externalclass
{mso-style-name:externalclass;
mso-margin-top-alt:auto;
margin-right:0cm;
mso-margin-bottom-alt:auto;
margin-left:0cm;
font-size:12.0pt;
font-family:"Times New Roman","serif";}
span.headtext
{mso-style-name:head_text;}
span.applelinksorange
{mso-style-name:applelinksorange;}
span.EmailStyle23
{mso-style-type:personal-reply;
font-family:"Calibri","sans-serif";
color:#1F497D;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:10.0pt;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:72.0pt 72.0pt 72.0pt 72.0pt;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]--></head><body bgcolor=white lang=EN-CA link="#6E7176" vlink="#6E7176"><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Hi all: <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>See below for an interesting article found by Michael.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Thx.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Glen<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><o:p> </o:p></p><div><div><div><p class=MsoNormal><span style='font-size:14.0pt;font-family:"Arial","sans-serif";color:blue'><o:p> </o:p></span></p></div><div><div><div><div><p class=MsoNormal><span style='font-size:13.5pt;font-family:"Arial","sans-serif";color:blue'>Lots more potential tests in the “future”!</span><span style='font-size:14.0pt;font-family:"Arial","sans-serif";color:blue'><o:p></o:p></span></p></div><div><div><p class=MsoNormal><span style='font-family:"Calibri","sans-serif";color:black'><o:p> </o:p></span></p></div><div><div><div><p class=MsoNormal style='background:whitesmoke'><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black'><o:p> </o:p></span></p></div></div></div><div><p class=MsoNormal><span style='font-family:"Calibri","sans-serif";color:black'><o:p> </o:p></span></p></div></div><div><p class=MsoNormal align=center style='text-align:center'><span style='font-size:7.5pt;font-family:"Arial","sans-serif";color:black'>If you are unable to see the message below, <a href="http://links.remedyhealthmedia.mkt5226.com/servlet/MailView?ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0">click here to view</a>.</span><span style='font-family:"Calibri","sans-serif";color:black'><o:p></o:p></span></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#292F36;MAX-WIDTH: 675px;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:#292F36;border-collapse:collapse;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%'><tr><td width=675 style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:#292F36'><tr style='height:48.75pt'><td width=335 style='width:251.25pt;padding:0cm 0cm 0cm 0cm;height:48.75pt'><p class=MsoNormal align=center style='text-align:center'><a name=logo></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=15&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><span style='text-decoration:none'><img border=0 width=180 id=z7tgzzdpam src="http://email.rmdy.hm/ha50/nl/ha50logo.png" alt=logo></span></a><o:p></o:p></p></td><td width=340 style='width:255.0pt;padding:0cm 0cm 0cm 0cm;height:48.75pt'><p class=MsoNormal align=center style='text-align:center;line-height:18.0pt;mso-line-height-rule:exactly'><a name="www_healthafter50_com_"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=4&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><strong><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#D2232A;text-decoration:none'>HOME</span></strong></a><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:white'> | <a name="www_healthafter50_com_store"></a></span><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=16&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><strong><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:white;text-decoration:none'>BOOKSTORE</span></strong></a><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:white'> | <a name="Forward_To_Friend"></a></span><a href="http://www.pages02.net/remedyhealthmediallc/Hopkins_FTF/Hopkins_FTF?spMailingID=9959039&spUserID=MTQxMTQwMDExMDU3S0&spJobID=MTA0MjMxMjI0MgS2&spReportId=MTA0MjMxMjI0MgS2"><strong><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#D2232A;text-decoration:none'>SHARE</span></strong></a><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:white'><o:p></o:p></span></p></td></tr></table></div></td></tr></table></td></tr></table></div></td></tr></table></div><p class=MsoNormal align=center style='text-align:center'><span style='font-family:"Calibri","sans-serif";color:black'><o:p> </o:p></span></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white;MAX-WIDTH: 675px;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:white;border-collapse:collapse'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white'><tr><td width=675 style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:white;border-collapse:collapse'><tr><td width=675 valign=top style='width:506.25pt;padding:11.25pt 0cm 11.25pt 0cm'><p class=MsoNormal align=center style='text-align:center'><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=4&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><span style='color:#D2232A;text-decoration:none'><img border=0 height=60 id="_x0000_i1026" src="http://email.rmdy.hm/ha50images/E_Images/Prostate_Health_RED_Banner.png" alt="Please download pictures"></span></a><o:p></o:p></p></td></tr></table></div><p class=MsoNormal><span style='display:none'><o:p> </o:p></span></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:white;MIN-WIDTH: 675px'><tr><td width=675 valign=top style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><a name="Prostate_Main_Story_Image"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=13&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><span style='text-decoration:none'><img border=0 id="_x0000_i1027" src="http://email.rmdy.hm/ha50images/E_Images/2016_11_30_Prostate_M.jpg" alt="Please Download Pictures"></span></a><o:p></o:p></p></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><em><span style='font-size:7.5pt;color:white'>ThinkstockPhotos</span></em><span style='font-size:7.5pt;color:white'><o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white'><tr><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td><td width=625 valign=top style='width:468.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:21.0pt;font-family:"Helvetica","sans-serif";color:#D2232A'>How Effective Are Prostate Cancer Tests?<o:p></o:p></span></p></td><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td></tr></table></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td><td style='border:none;padding:0cm 0cm 0cm 0cm' width=650 colspan=2><p class='MsoNormal'> </td></tr><tr><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td><td width=625 valign=top style='width:468.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal style='line-height:15.0pt'><span style='font-family:"Helvetica","sans-serif";color:#312E2A'>We are still waiting for a test that can—with complete accuracy—distinguish between men who have prostate cancer and those who are cancer-free. If prostate cancer is diagnosed, the test should also determine whether it's an aggressive form that requires prompt treatment or a slow-growing tumor that may only need close monitoring.<br><br>A number of companies have introduced tests that could take us closer to that goal, but there's still much to be learned about them and their proper role in the management of prostate cancer. Unfortunately, published studies are limited, and so far none of the tests has a long-term track record in the real world, where doctors screen, counsel, and treat patients.<br><br>Once a particular test has been approved by the Food and Drug Administration and is available, it can be marketed without proof of benefit. Furthermore, unsubstantiated claims abound for many tests. For now, all of these tests are intended to augment—not replace—a doctor's clinical judgment along with the existing proven tests currently used to screen for and monitor prostate cancer.<br><br>Time will tell if any of these new tests add information that will significantly affect treatment decisions. Here's an overview of the latest prostate cancer tests—and the questions we hope they can answer. All of the tests are available in the U.S. unless otherwise indicated.<br><br></span><strong><span style='font-size:13.5pt;font-family:"Helvetica","sans-serif";color:black'>Tests to indicate the need for a prostate biopsy</span></strong><span style='font-family:"Helvetica","sans-serif";color:#312E2A'><br>An elevated prostate-specific antigen (PSA) level can indicate that a man has prostate cancer; however, findings may also be elevated in men with less serious conditions, such as benign prostatic hyperplasia (BPH), also known as benign prostatic enlargement (BPE). Yet most men with elevated PSA levels end up having an anxiety-provoking biopsy to rule out cancer. Two new tests show great promise in identifying appropriate biopsy candidates with greater accuracy:<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>The Prostate Health Index.</span></strong> Commonly known as the phi test, measures blood levels of PSA, free PSA, and a precursor (or early form) of PSA, known as pro-PSA or p2PSA. Research suggests that pro-PSA levels are a better indicator of prostate cancer than total or free PSA levels and that men with elevated pro-PSA levels are at high risk for having an aggressive form of prostate cancer. Using a mathematical equation, the phi test combines all three variants to better determine whether prostate cancer is present.<br><br>The test is indicated for use in men age 50 and older whose digital rectal exam showed no signs of cancer and who have a total PSA value between 4 ng/mL and 10 ng/mL—a gray zone that could indicate prostate cancer or a less serious condition such as BPH. Like the other tests described herein, the phi test doesn't deliver a definitive answer about what action to take—in this case, whether or not to have a biopsy.<br><br>Instead, the phi test's results, which are scored from 0 to 55 and above, reflect the probability that a biopsy will detect cancer. For example, a phi test score below 27 is associated with a 9.8 percent probability that prostate cancer is present, while a score of 55 or more suggests a likelihood of greater than 50 percent. As with all of the tests, phi test results must be considered in light of a man's other risk factors.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>4Kscore.</span></strong> This blood test (currently available in Europe and Mexico) measures levels of three PSA variants (total PSA, free PSA, and intact PSA), plus an enzyme called human kallikrein 2 (hK2), which is elevated in men with prostate cancer. Some scientists believe hK2 may promote the growth and spread of prostate cancer. The 4Kscore also uses a mathematical algorithm to calculate the risk of prostate cancer in a man with an elevated PSA level.<o:p></o:p></span></p></td><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td><td style='padding:0cm 0cm 0cm 0cm'></td><td style='padding:0cm 0cm 0cm 0cm'></td></tr></table></td></tr></table></div></td></tr></table></td></tr></table></div><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC;MAX-WIDTH: 675px;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:#CCCCCC;border-collapse:collapse;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC'><tr><td width=675 style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:#CCCCCC'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td width=675 valign=top style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><a name="Prostate_WHP_Image_snow_runner_close_up"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=17&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><span style='text-decoration:none'><img border=0 id="_x0000_i1028" src="http://email.rmdy.hm/ha50images/E_Images/2017_Prostate_WHP_TImage_675_002NTS_NEW.jpg" alt="Please Download Pictures"></span></a><o:p></o:p></p></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><em><span style='font-size:7.5pt;color:black'>ThinkstockPhotos</span></em><span style='font-size:7.5pt;color:black'><o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC'><tr><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td><td width=625 valign=top style='width:468.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:21.0pt;font-family:"Helvetica","sans-serif";color:#D2232A'>2017 Prostate Disorders White Paper<o:p></o:p></span></p></td><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td></tr></table></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC'><tr><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td><td width=625 valign=top style='width:468.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal style='line-height:15.0pt'><span style='font-family:"Helvetica","sans-serif";color:#312E2A'>Did you know... Having sex within 72 hours of your PSA test can produce a false reading? ED can be a symptom of prostate cancer? By age 70, the average man's prostate has doubled in size. Early detection of prostate cancer is a KEY factor in treating this disease successfully. Being fully informed is also important and that's where the <strong><span style='font-family:"Helvetica","sans-serif"'>2017 Prostate Disorders White Paper</span></strong> comes in.<o:p></o:p></span></p></td><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td></tr></table></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%'><tr><td width=22 valign=top style='width:16.5pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td><td width=150 style='width:112.5pt;padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0><tr><td valign=top style='border:solid #B73326 1.0pt;background:#057B20;padding:7.5pt 7.5pt 7.5pt 7.5pt;border-radius: 5px;-moz-border-radius: 5px;-webkit-border-radius: 5px'><p class=MsoNormal align=center style='text-align:center'><a name="Prostate_WHP_Button"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=9&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><b><span style='font-family:"Verdana","sans-serif";color:white;text-decoration:none'>ORDER NOW</span></b></a><b><span style='font-size:9.0pt;font-family:"Georgia","serif";color:white'><o:p></o:p></span></b></p></td></tr></table></td><td width=415 style='width:311.25pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td></tr></table></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr></table></div></td></tr></table></td></tr></table></div></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white;MAX-WIDTH: 675px;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:white;border-collapse:collapse;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white'><tr><td width=675 style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:white'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white'><tr><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td><td width=625 valign=top style='width:468.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal style='line-height:15.0pt'><strong><span style='font-size:13.5pt;font-family:"Helvetica","sans-serif";color:black'>Tests to rule out a repeat biopsy</span></strong><span style='font-family:"Helvetica","sans-serif";color:#312E2A'><br>Some prostate biopsies produce inconclusive results. Others may be negative even in men with elevated PSA or other high-risk features. Typically, this means the procedure must be repeated even though only 10 to 36 percent of second biopsies detect cancer. The following tests can be used to help determine the need for a repeat biopsy.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>Progensa.</span></strong> This urine test detects the presence of a gene called prostate cancer antigen 3 (PCA3). This gene is overexpressed (or overactive) in 95 percent of men with prostate cancer, but not in men who have healthy prostates or BPH. Results are ranked from less than 5 to greater than 100, with a score of less than 25 indicating a decreased likelihood of a positive biopsy. Progensa is approved for use in men age 50 and older who have had one or more negative biopsies, but who a doctor nonetheless suspects may have prostate cancer.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>ConfirmMDx.</span></strong> Whether a particular gene is turned "off" or "on" can be determined by the presence or absence of specific chemical tags or methyl groups—methylation—of DNA, the building blocks of genes. When this process of DNA methylation turns off the activity of tumor suppressor genes, cancer may develop. Based on technology developed at Johns Hopkins and other institutions, ConfirmMDx analyzes the DNA methylation status of a man's biopsied prostate tissue. Test results indicate that the biopsy specimen is positive or negative for methylation. A positive finding, which is mapped on a diagram of the prostate, suggests the need for a repeat biopsy.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>Prostate Core Mitomic Test.</span></strong> This test analyzes a man's biopsied prostate tissue, looking for damage to mitochrondrial DNA (mtDNA) caused by cellular changes associated with prostate cancer development. A negative result suggests that the man is at low risk of undiagnosed prostate cancer and that a repeat biopsy can be deferred.<br><br></span><strong><span style='font-size:13.5pt;font-family:"Helvetica","sans-serif";color:black'>Tests to determine the need for prostate cancer treatment</span></strong><span style='font-family:"Helvetica","sans-serif";color:#312E2A'><br>Many men with positive biopsies have low-risk tumors that won't spread to other organs and become deadly. For some of these men, active surveillance may be a reasonable alternative to immediate treatment, but standard diagnostic tools are imperfect at distinguishing between indolent and aggressive tumors. Results from the following tests, when combined with a Gleason score and other clinical information, are intended to help provide reassurance about the decision to forgo or institute immediate treatment.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>Prolaris.</span></strong> This test uses a sample of tumor tissue removed during a biopsy and measures how rapidly cells are dividing as a way to gauge whether the tumor is more or less likely to be deadly. Prolaris scores range from -1.3 to +4.7 and are stratified by risk, with higher scores indicating a greater risk of dying from prostate cancer.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>ProstaVysion.</span></strong> For this test, biopsied tissue is analyzed for the presence of two genetic biomarkers for prostate cancer. One biomarker, known as TMPRSS2:ERG, is a fusion of two genes and is associated with the presence of prostate cancer. The other biomarker, PTEN, is a "suppressor" gene that normally helps keep certain forms of cancer in check and is missing in 60 percent of men with metastatic prostate cancer. By examining those two markers, the test provides a molecular analysis of prostate cancer aggressiveness and the patient's long-term prognosis.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>Oncotype DX.</span></strong> This test examines the interactions between 17 genes in a biopsy sample to predict whether a tumor is likely to be aggressive. The result, the Genomic Prostate Score, ranges from 0 to 100; a low score suggests that the tumor is less likely to grow and spread and aggressive treatment may not be necessary. Conversely, a higher score suggests a poorer prognosis and a greater need for immediate treatment.<br><br></span><strong><span style='font-size:13.5pt;font-family:"Helvetica","sans-serif";color:black'>Tests to determine the need for treatment after prostate surgery</span></strong><span style='font-family:"Helvetica","sans-serif";color:#312E2A'><br>Some men who have had a radical prostatectomy are at risk for recurrence and would benefit from additional therapies, such as radiation or hormone therapy, but identifying them is a challenge. At least one of the tests discussed above, Prolaris, as well as the tests below, may be able to help with that challenge.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>NADiA ProsVue.</span></strong> This blood test measures the rate of tiny changes in PSA levels over time, which can suggest that a man is at risk for recurrence. Patients are categorized as at reduced risk, which indicates that a man is at a lower risk for clinical (not biochemical) cancer recurrence for several years following his prostatectomy, or not at reduced risk.<br><br>• <strong><span style='font-family:"Helvetica","sans-serif"'>Decipher.</span></strong> This test, which is not yet available in the U.S., analyzes tissue from the prostate tumor to look for 22 genes linked to prostate cancer metastasis. The results, which are presented as a percentage score, indicate whether a man is at high or low risk for metastases and, therefore, whether further treatment should be considered.<br><br></span><strong><span style='font-size:13.5pt;font-family:"Helvetica","sans-serif";color:black'>Test costs</span></strong><span style='font-family:"Helvetica","sans-serif";color:#312E2A'><br>Since these tests are relatively new, you may need to pay out of pocket. While some insurers cover the costs of some tests, coverage varies. Before having one of these tests (which can run to four figures), check with your insurer first. Also be sure to check with the test's manufacturer; some offer assistance with test fees.<o:p></o:p></span></p></td><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td><td style='padding:0cm 0cm 0cm 0cm'></td><td style='padding:0cm 0cm 0cm 0cm'></td></tr></table></td></tr></table></div></td></tr></table></td></tr></table></div><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC;MAX-WIDTH: 675px;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:#CCCCCC;border-collapse:collapse;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC'><tr><td width=675 style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:#CCCCCC'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td width=675 valign=top style='width:506.25pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><a name="Prostate_WHP_Image_snow_runner_towards"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=18&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><span style='text-decoration:none'><img border=0 id="_x0000_i1029" src="http://email.rmdy.hm/ha50images/E_Images/2017_Prostate_WHP_TImage_675_004NTS_NEW.jpg" alt="Please Download Pictures"></span></a><o:p></o:p></p></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><em><span style='font-size:7.5pt;color:black'>ThinkstockPhotos</span></em><span style='font-size:7.5pt;color:black'><o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC'><tr><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td><td width=625 valign=top style='width:468.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:21.0pt;font-family:"Helvetica","sans-serif";color:#D2232A'>2017 Prostate Disorders White Paper<o:p></o:p></span></p></td><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td></tr></table></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#CCCCCC'><tr><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td><td width=625 valign=top style='width:468.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal style='line-height:15.0pt'><span style='font-family:"Helvetica","sans-serif";color:#312E2A'>Did you know... Having sex within 72 hours of your PSA test can produce a false reading? ED can be a symptom of prostate cancer? By age 70, the average man's prostate has doubled in size. Early detection of prostate cancer is a KEY factor in treating this disease successfully. Being fully informed is also important and that's where the <strong><span style='font-family:"Helvetica","sans-serif"'>2017 Prostate Disorders White Paper</span></strong> comes in.<o:p></o:p></span></p></td><td width=25 valign=top style='width:18.75pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> <o:p></o:p></span></p></td></tr></table></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%'><tr><td width=22 valign=top style='width:16.5pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td><td width=150 style='width:112.5pt;padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0><tr><td valign=top style='border:solid #B73326 1.0pt;background:#057B20;padding:7.5pt 7.5pt 7.5pt 7.5pt;border-radius: 5px;-moz-border-radius: 5px;-webkit-border-radius: 5px'><p class=MsoNormal align=center style='text-align:center'><a name="Prostate_WHP_Button_1"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=11&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><b><span style='font-family:"Verdana","sans-serif";color:white;text-decoration:none'>ORDER NOW</span></b></a><b><span style='font-size:9.0pt;font-family:"Georgia","serif";color:white'><o:p></o:p></span></b></p></td></tr></table></td><td width=415 style='width:311.25pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td></tr></table></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'></td></tr></table></div></td></tr></table></td></tr></table></div></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#666666'><tr><td width="100%" style='width:100.0%;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt;background:#666666;border-collapse:collapse;MIN-WIDTH: 675px'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt'><tr><td width=40 valign=top style='width:30.0pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td><td width=340 valign=top style='width:255.0pt;padding:6.0pt 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='mso-line-height-alt:11.25pt'><b><span style='font-size:13.0pt;font-family:"Helvetica","sans-serif";color:#4EA3D9'>Newsletter Options<o:p></o:p></span></b></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:11.25pt'><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'>This email was sent to <a name="_EMAIL_"></a><a href="mailto:michael@wilsonlink.com"><b><span style='color:#4EA3D9;text-decoration:none'>michael@wilsonlink.com</span></b></a><o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:11.25pt'><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'>We're happy to help you <a name="optout_all"></a><a href="http://www.pages02.net/remedyhealthmediallc/PreferenceOptOutAll/PreferenceOptOutAll?spMailingID=9959039&spUserID=MTQxMTQwMDExMDU3S0&spJobID=MTA0MjMxMjI0MgS2&spReportId=MTA0MjMxMjI0MgS2" target="_blank"><b><span style='color:#4EA3D9;text-decoration:none'>unsubscribe</span></b></a>.<o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:13.5pt'><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'>If this email was forwarded to you by another email recipient and you would like to subscribe, <a href="http://www.pages02.net/remedyhealthmediallc/Hopkins_FTF/Hopkins_FTF?spMailingID=9959039&spUserID=MTQxMTQwMDExMDU3S0&spJobID=MTA0MjMxMjI0MgS2&spReportId=MTA0MjMxMjI0MgS2" target="_blank"><b><span style='color:#4EA3D9;text-decoration:none'>click here.</span></b></a><o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:13.5pt'><a name="Privacy_Policy"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=8&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><b><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:#4EA3D9;text-decoration:none'>Click here</span></b></a><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> to view our privacy policy.<o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 7.5pt 0cm'><p class=MsoNormal style='line-height:11.25pt'><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'>This information is not intended to substitute for the advice of a physician.<o:p></o:p></span></p></td></tr></table></td><td width=15 valign=top style='width:11.25pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td><td width=290 style='width:217.5pt;padding:6.0pt 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:11.25pt;mso-line-height-rule:exactly'><b><span style='font-size:11.5pt;font-family:"Helvetica","sans-serif";color:#4EA3D9'>Contact Us<o:p></o:p></span></b></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:13.5pt;mso-line-height-rule:exactly'><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'>Need to contact us? <a name="Contact_Us_Page"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=1&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><b><span style='color:#4EA3D9;text-decoration:none'>Click here</span></b></a><o:p></o:p></span></p></td></tr><tr><td style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:11.25pt;mso-line-height-rule:exactly'><b><span style='font-size:11.5pt;font-family:"Helvetica","sans-serif";color:#4EA3D9'>The Remedy Health Network<o:p></o:p></span></b></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:11.25pt;mso-line-height-rule:exactly'><a name="Berkeley_Wellness"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=2&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><b><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:#4EA3D9;text-decoration:none'>Berkeley Wellness:</span></b></a><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> science-backed, expert-vetted health and wellness advice<o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:11.25pt;mso-line-height-rule:exactly'><a name=HealthCentral></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=12&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><b><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:#4EA3D9;text-decoration:none'>HealthCentral:</span></b></a><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> condition news and advice from the community that helps you live your best life<o:p></o:p></span></p></td></tr><tr><td valign=top style='padding:9.0pt 0cm 0cm 0cm'><p class=MsoNormal style='line-height:11.25pt;mso-line-height-rule:exactly'><a name=TheBody></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=3&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0"><b><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:#4EA3D9;text-decoration:none'>The Body:</span></b></a><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'> timely HIV/AIDS news, information, support and community<o:p></o:p></span></p></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal style='line-height:18.75pt;mso-line-height-rule:exactly'> <o:p></o:p></p></td></tr></table></td><td width=40 valign=top style='width:30.0pt;padding:0cm 0cm 0cm 0cm'><p class=MsoNormal> <o:p></o:p></p></td></tr></table></div></td></tr></table></div></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#292F36'><tr><td width="100%" style='width:100.0%;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=675 style='width:506.25pt'><tr style='height:3.75pt'><td width="100%" style='width:100.0%;padding:0cm 0cm 0cm 0cm;height:3.75pt'><p class=MsoNormal style='mso-line-height-alt:3.75pt'> <o:p></o:p></p></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><div><p class=MsoNormal align=center style='text-align:center;line-height:16.5pt'><a name="footer_logo"></a><a href="https://www.healthafter50.com/"><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";text-decoration:none'><img border=0 width=180 id="_x0000_i1030" src="http://email.rmdy.hm/ha50/nl/ha50logo.png" alt=logo></span></a><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'><o:p></o:p></span></p></div><p class=MsoNormal align=center style='text-align:center;line-height:16.5pt'><span style='font-size:10.5pt;font-family:"Helvetica","sans-serif";color:white'>© 2016 <a name="0.1_www_remedyhealthmedia_com"></a><a href="http://links.remedyhealthmedia.mkt5226.com/ctt?kn=10&ms=OTk1OTAzOQS2&r=MTQxMTQwMDExMDU3S0&b=0&j=MTA0MjMxMjI0MgS2&mt=1&rt=0" target="_blank"><strong><span style='font-family:"Helvetica","sans-serif";color:#4EA3D9;text-decoration:none'>Remedy Health Media, LLC</span></strong></a> ALL RIGHTS RESERVED<br>750 Third Avenue 6th Floor New York, NY 10017 <o:p></o:p></span></p></td></tr><tr style='height:3.75pt'><td width="100%" style='width:100.0%;padding:0cm 0cm 0cm 0cm;height:3.75pt'><p class=MsoNormal style='mso-line-height-alt:3.75pt'> <o:p></o:p></p></td></tr></table></div></td></tr></table></td></tr></table></td></tr></table></div><p class=MsoNormal><span style='font-family:"Calibri","sans-serif";color:black'><img border=0 id="_x0000_i1031" src="http://links.remedyhealthmedia.mkt5226.com/open/log/9959039/MTQxMTQwMDExMDU3S0/0/MTA0MjMxMjI0MgS2/1/0"><o:p></o:p></span></p></div></div></div></div></div></div></div></body></html>