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</o:shapelayout></xml><![endif]--></head><body bgcolor="#FAFAFA" lang=EN-CA link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Hi all:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>See e-mail below from PCC.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Thx.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Glen<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div><div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm'><p class=MsoNormal><b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> Rocco Rossi <o:p></o:p></span></p><p class=MsoNormal><b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>Subject:</span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> How You Helped Break Prostate Cancer’s Genetic Code<o:p></o:p></span></p></div></div><p class=MsoNormal><o:p> </o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#FAFAFA;border-collapse:collapse'><tr><td width="100%" valign=top style='width:100.0%;padding:7.5pt 7.5pt 7.5pt 7.5pt'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;border-collapse:collapse'><tr><td width=600 valign=top style='width:450.0pt;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='background:#FAFAFA;padding:6.75pt 0cm 6.75pt 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:6.75pt 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;margin-left:-2.25pt;margin-right:-2.25pt'><tr><td width=299 valign=top style='width:224.25pt;padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:0cm 13.5pt 6.75pt 13.5pt'><p class=MsoNormal style='mso-margin-top-alt:7.5pt;margin-right:0cm;margin-bottom:7.5pt;margin-left:0cm;line-height:150%'><span style='font-size:9.0pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#656565'>How You Helped Break Prostate Cancer’s Genetic Code<o:p></o:p></span></p></td></tr></table></td><td width=299 valign=top style='width:224.25pt;padding:0cm 0cm 0cm 0cm;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:break-word'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;max-width: 299px;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:0cm 13.5pt 6.75pt 13.5pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal align=right style='text-align:right;line-height:150%'><span style='font-size:9.0pt;line-height:150%;font-family:"Helvetica","sans-serif";color:#656565'><a href="http://us2.campaign-archive1.com/?u=381dca877e43c44046caa6dd1&id=6fd5763ea3&e=b7e2b89435" target="_blank"><span style='color:#656565'>View this email in your browser</span></a><o:p></o:p></span></p></td></tr></table></td></tr></table></td></tr></table></td></tr><tr><td valign=top style='background:white;padding:6.75pt 0cm 0cm 0cm;background:cover;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;background-size: cover;background-position-x:50%;background-position-y:50%' id=templateHeader><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal align=center style='text-align:center'><a href="http://prostatecancer.us2.list-manage1.com/track/click?u=381dca877e43c44046caa6dd1&id=99c3dc1a32&e=b7e2b89435" target="_blank" title=""><span style='text-decoration:none'><img border=0 width=599 id="_x0000_i1025" src="https://gallery.mailchimp.com/381dca877e43c44046caa6dd1/images/acc7aa7b-4191-4972-ad51-106a501fc1a8.jpg"></span></a><o:p></o:p></p></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:6.75pt 0cm 0cm 0cm;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;margin-left:-2.25pt;margin-right:-2.25pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td width=599 valign=top style='width:449.25pt;padding:0cm 0cm 0cm 0cm;max-width: 100%;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:break-word'><tr><td valign=top style='padding:0cm 13.5pt 6.75pt 13.5pt'><p class=MsoNormal style='line-height:150%'><span style='font-family:"Helvetica","sans-serif";color:#202020'>Dear Friend, <br><br>Did you hear the news? Researchers have made an important discovery that promises to <em><span style='font-family:"Helvetica","sans-serif"'>revolutionize</span></em> how prostate cancer is treated!<br><br>Maybe you saw it in the headlines -- the exciting buzz surrounding a key finding published recently in the highly-respected scientific journal <em><span style='font-family:"Helvetica","sans-serif"'>Nature</span></em>.<br><br><strong><span style='font-family:"Helvetica","sans-serif"'>In case you missed it, I want to deliver the news personally -- because <a href="http://prostatecancer.us2.list-manage.com/track/click?u=381dca877e43c44046caa6dd1&id=f1551e54cb&e=b7e2b89435" target="_blank"><span style='color:#1E65A5'>your support for Prostate Cancer Canada is critical</span></a> to what happens next.</span></strong><br> <o:p></o:p></span></p></td></tr></table></td></tr></table></td></tr></table></td></tr><tr><td valign=top style='background:white;padding:0cm 0cm 0cm 0cm;background:cover;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;background-size: cover;background-position-x:50%;background-position-y:50%' id=templateUpperBody><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:0cm 13.5pt 13.5pt 13.5pt;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='background:#2664AF;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td style='padding:11.25pt 11.25pt 11.25pt 11.25pt;border-radius: 3px;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><p class=MsoNormal align=center style='text-align:center'><span style='font-family:"Arial","sans-serif"'><a href="http://prostatecancer.us2.list-manage.com/track/click?u=381dca877e43c44046caa6dd1&id=4b7e512e03&e=b7e2b89435" target="_blank" title="Donate Now"><b><span style='color:white;text-decoration:none'>Donate Now</span></b></a> <o:p></o:p></span></p></td></tr></table></div></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:6.75pt 0cm 0cm 0cm;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;margin-left:-2.25pt;margin-right:-2.25pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td width=599 valign=top style='width:449.25pt;padding:0cm 0cm 0cm 0cm;max-width: 100%;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:break-word'><tr><td valign=top style='padding:0cm 13.5pt 6.75pt 13.5pt'><p class=MsoNormal style='line-height:150%'><span style='font-family:"Helvetica","sans-serif";color:#202020'>With funding from Prostate Cancer Canada, researchers led by Drs. Robert Bristow and Paul Boutros have made a key discovery: <strong><span style='font-family:"Helvetica","sans-serif"'>determining when cancers that seem non-aggressive harbour the potential to become aggressive by using the cancer's own genetic fingerprint.</span></strong><br><br>This critical insight will pave the way for the development of tests that will enable men to know their exact risk at the point of diagnosis, allowing for the most personalized, most effective treatment possible.<br><br><strong><span style='font-family:"Helvetica","sans-serif"'>This is a real game-changer, and it wouldn't have been possible without people like you. But <a href="http://prostatecancer.us2.list-manage.com/track/click?u=381dca877e43c44046caa6dd1&id=a4331e25a9&e=b7e2b89435" target="_blank"><span style='color:#1E65A5'>your support now is key to saving lives with this breakthrough!</span></a></span></strong><br><br>With your gift, you'll help us take the next step -- translating scientific discovery into life-saving clinical practice.<br><br>Being able to gauge cancer's aggressiveness as early as possible is a critical first step to more personalized care. As Dr. Bristow explains, that may mean dialing back treatment for men with less aggressive cancers and intensifying treatment for those with aggressive cancers.<br><br>"We hope that this research mode of testing will now go into the clinical mode in the next two to five years, and really change clinical practice for men with prostate cancer in Canada and worldwide," says Dr. Bristow. <o:p></o:p></span></p><p class=MsoNormal align=center style='text-align:center;line-height:150%'><span style='font-family:"Helvetica","sans-serif";color:#202020'><br><strong><span style='font-family:"Helvetica","sans-serif"'>Your support today will help make that happen.</span></strong><o:p></o:p></span></p><p class=MsoNormal style='line-height:150%'><span style='font-family:"Helvetica","sans-serif";color:#202020'><br><em><span style='font-family:"Helvetica","sans-serif"'>Despite incredible progress, prostate cancer still kills approximately 4,000 Canadian men each year. Imagine the lives that could be saved -- and the quality of life that could be preserved by putting this breakthrough to work as soon as possible.</span></em><br><br><strong><span style='font-family:"Helvetica","sans-serif"'>Please, help take the next step toward giving hope to men and their families with <a href="http://prostatecancer.us2.list-manage.com/track/click?u=381dca877e43c44046caa6dd1&id=e91b610d74&e=b7e2b89435" target="_blank"><span style='color:#1E65A5'>your gift of $50 ... $100 ... $150 or more now!</span></a> For your life-saving support...</span></strong><br><br>Thank you! <o:p></o:p></span></p></td></tr></table></td></tr></table></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%'><tr><td valign=top style='padding:6.75pt 6.75pt 6.75pt 6.75pt;-ms-text-size-adjust: 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