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</o:shapelayout></xml><![endif]--></head><body lang=EN-CA link=blue vlink="#954F72"><div class=WordSection1><p class=MsoNormal>Hi all:</p><p class=MsoNormal>Interesting article below.</p><p class=MsoNormal>Thx.</p><p class=MsoNormal>Glen</p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>Sent from <a href="https://go.microsoft.com/fwlink/?LinkId=550986">Mail</a> for Windows 10</p><p class=MsoNormal><o:p> </o:p></p><div style='mso-element:para-border-div;border:none;border-top:solid #E1E1E1 1.0pt;padding:3.0pt 0cm 0cm 0cm'><p class=MsoNormal style='border:none;padding:0cm'><b>From: </b><a href="mailto:cancernetwork@email.cmpmedica-usa.com">Cancer Network</a><br><b>Sent: </b>February 9, 2018 3:32 PM<br><b>To: </b><a href="mailto:glen46nor@gmail.com">glen46nor@gmail.com</a><br><b>Subject: </b>ASCO GU: Enzalutamide Delays Metastasis in Castration-ResistantProstate Cancer</p></div><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><span style='font-size:1.0pt;display:none'>Clinical model predicts survival for atezolizumab in bladder cancer<o:p></o:p></span></p><div id=wrapper><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal align=center style='margin-bottom:12.0pt;text-align:center'><span style='font-size:7.5pt;font-family:"Arial",sans-serif;color:#333333'>To view this email as a web page, click <a href="http://view.email.cmpmedica-usa.com/?qs=5324ed74d3fe22c60c738c4bedf73de216f14bc74a9e5dfffe3791063ddfdbc0c95606006b5950e0f1ad32e883bc84b5968a6fb72797e28f99e49431d34c8599c1c8a258840cc172cf54fd6643cbfc7b"><b><span style='font-size:8.5pt;color:#056C9C'>here.</span></b></a></span><o:p></o:p></p></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#333333;border-spacing: 0'><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:#333333;border-collapse:collapse'><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><img border=0 width=220 height=20 style='width:2.2916in;height:.2083in' id="_x0000_i1034" src="http://www.ubmmedica.com/wp-content/uploads/2016/11/ModernMedicineNetwork-small.png" alt="Modern Medicine Network"><o:p></o:p></p></td></tr></table></div></td></tr></table></div><p class=MsoNormal><span style='display:none'><o:p> </o:p></span></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse;border-spacing: 0;min-width: 600px'><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><a href="http://click.email.cmpmedica-usa.com/?qs=46f42cead5de7f364df88f2d4fd955be820e1d6b77692ef029f14bd806cf054b5653b9c392bc908a0033e51c81e596b7"><span style='color:#295AA6;text-decoration:none'><img border=0 width=360 height=69 style='width:3.75in;height:.7187in' id="_x0000_i1033" src="http://images.ubmmedica.com/newsletters/Logos/CancerNetworkLogo.png" alt="Cancer Network"></span></a><o:p></o:p></p></td></tr><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><a href="http://click.email.cmpmedica-usa.com/?qs=46f42cead5de7f368f9c718b0b8c96900e137ab84c445a61af42f2ae77870c461718fb19384414244da8a007fb939d28"><span style='color:#295AA6;text-decoration:none'><img border=0 width=600 height=120 style='width:6.25in;height:1.25in' id="_x0000_i1032" src="http://content.ubmlifesciences.com/sites/default/files/conference-insider-GU-meeting-NL-banner-2018.jpg" alt="Cancer Network"></span></a><o:p></o:p></p></td></tr></table></div><p class=MsoNormal><span style='display:none'><o:p> </o:p></span></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:#1A357D;border-collapse:collapse;border-spacing: 0;min-width: 600px'><tr><td style='padding:7.5pt 7.5pt 7.5pt 7.5pt'><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Arial",sans-serif;color:white'>ASCO GU 2018 | February 9, 2018 <o:p></o:p></span></p></td></tr></table></div><p class=MsoNormal><span style='display:none'><o:p> </o:p></span></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse;border-spacing: 0;min-width: 600px'><tr style='height:1.5pt'><td style='padding:0cm 0cm 0cm 0cm;height:1.5pt'><p class=MsoNormal> <o:p></o:p></p></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width=270 style='width:202.5pt;border-collapse:collapse;border-spacing: 0' id=articles><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><a href="http://click.email.cmpmedica-usa.com/?qs=46f42cead5de7f36287f9185a4357726bec812e7bc6f5e59ab85d96b2e6e3132f656652279622254c42856d588ebde79"><b><span style='font-size:12.5pt;font-family:"Arial",sans-serif;color:#056C9C'>Enzalutamide Delays Metastasis in Castration-Resistant Prostate Cancer</span></b></a> <o:p></o:p></p></td></tr><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333'>Enzalutamide resulted in a 71% reduction in metastatic disease risk among men with castration-resistant prostate cancer and rapid prostate-specific antigen doubling time, according to the first interim analysis of data from the phase III PROSPER trial. <o:p></o:p></span></p></td></tr><tr style='height:1.5pt'><td style='padding:3.75pt 3.75pt 3.75pt 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href="http://click.email.cmpmedica-usa.com/?qs=46f42cead5de7f363a590bb588f7e4a712e5f2d51c85ce9258cd2e10f75b8d1753dd1103bca124ba6bc951c9e870948b"><b><span style='font-size:12.5pt;font-family:"Arial",sans-serif;color:#056C9C'>Clinical Model Predicts Survival for Atezolizumab in Bladder Cancer</span></b></a> <o:p></o:p></p></td></tr><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='border-collapse:collapse;border-spacing: 0' id=articles><tr><td valign=top style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333'>A newly developed clinical model can predict overall survival for patients diagnosed with advanced bladder cancer who are treated with atezolizumab.<br><br></span><span style='font-size:11.5pt;font-family:"Arial",sans-serif;color:#333333'><a 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href="http://click.email.cmpmedica-usa.com/?qs=46f42cead5de7f36d28671da5581f2ad3fd4568bccf9d15e8ea495b62093f4e8e395873779ed9105154d6a010775e467"><b><span style='font-size:12.5pt;font-family:"Arial",sans-serif;color:#056C9C'>Could Experimental Gene Signature Predict Prostate Cancer Recurrence?</span></b></a> <o:p></o:p></p></td></tr><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 style='border-collapse:collapse;border-spacing: 0' id=articles><tr><td valign=top style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial",sans-serif;color:#333333'>Researchers are developing a prognostic hypoxia gene signature for patients with localized prostate cancer treated with prostatectomy that predicts biochemical failure and metastasis.<br><br></span><span style='font-size:11.5pt;font-family:"Arial",sans-serif;color:#333333'><a 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