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</o:shapelayout></xml><![endif]--></head><body bgcolor="#F0F1F2" lang=EN-CA link="#295AA6" vlink="#295AA6"><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Hi all:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>See the 1<sup>st</sup> topic below.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Thx.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Glen<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div><div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm'><p class=MsoNormal><b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> Cancer Network [mailto:cancernetwork@news.modernmedicine.com] <br><br><o:p></o:p></span></p></div></div><p class=MsoNormal><o:p> </o:p></p><div><p class=MsoNormal style='mso-line-height-alt:.75pt'><span style='font-size:1.0pt;color:#333333'>Updates from the Prostate Cancer Topic Resource Center <o:p></o:p></span></p></div><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;border-spacing: 0'><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal align=center style='margin-bottom:12.0pt;text-align:center'><span style='font-size:7.5pt;font-family:"Arial","sans-serif";color:#333333'>To view this email as a web page, click <a href="http://app.network.modernmedicine.com/e/es?s=727777198&e=8498&elqTrackId=8d3596275ab74237a25256944ec01499&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><b><span style='font-size:8.5pt;color:#056C9C'>here.</span></b></a></span><o:p></o:p></p></td></tr></table><p class=MsoNormal style='background:#F0F1F2'><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;border-spacing: 0'><tr><td style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#333333;border-spacing: 0'><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:#333333;border-collapse:collapse'><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><img border=0 width=220 id=networkLogo src="http://images.ubmmedica.com/newsletters/Logos/ModernMedicineNetwork-small.png" alt="Modern Medicine Network"><o:p></o:p></p></td></tr></table></div></td></tr></table></div><p>[ ] <o:p></o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse;border-spacing: 0;min-width: 600px'><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=5 cellpadding=0 style='background:white;border-spacing: 0'><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=363&elqTrackId=6b5d0c24f2bb413f97886fbf72713563&GUID=C49B511B-6B22-4FB4-B49E-BAAA68D63CCE&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><span style='text-decoration:none'><img border=0 width=360 id=logo src="http://images.ubmmedica.com/newsletters/Logos/CancerNetworkLogo.png" alt="Cancer Network"></span></a><o:p></o:p></p></td></tr></table></td><td style='padding:0cm 0cm 0cm 0cm'></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:#1A357D;border-spacing: 0'><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0><tr><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='background:#1A357D;border-collapse:collapse'><tr><td nowrap style='padding:7.5pt 7.5pt 7.5pt 7.5pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif";text-transform:uppercase'><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=42&elqTrackId=c8654a0993b543b4843df9d6621bbe1f&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><span style='color:white;text-decoration:none'>Videos</span></a> <o:p></o:p></span></p></td></tr></table></td><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='background:#1A357D;border-collapse:collapse;border-spacing: 0'><tr><td nowrap style='padding:7.5pt 7.5pt 7.5pt 7.5pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif";text-transform:uppercase'><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=41&elqTrackId=64575acfc3b841199c35fb92107541b6&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><span style='color:white;text-decoration:none'>News</span></a> <o:p></o:p></span></p></td></tr></table></td><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='background:#1A357D;border-collapse:collapse;border-spacing: 0'><tr><td nowrap style='padding:7.5pt 7.5pt 7.5pt 7.5pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif";text-transform:uppercase'><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=40&elqTrackId=361e2647e3b646f5848ad394a0574c7e&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><span style='color:white;text-decoration:none'>Topics</span></a> <o:p></o:p></span></p></td></tr></table></td><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='background:#1A357D;border-collapse:collapse;border-spacing: 0'><tr><td nowrap style='padding:7.5pt 7.5pt 7.5pt 7.5pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif";text-transform:uppercase'><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=39&elqTrackId=602bda35082e40c3af00d5b9532b0569&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><span style='color:white;text-decoration:none'>Image IQ</span></a> <o:p></o:p></span></p></td></tr></table></td><td style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='background:#1A357D;border-collapse:collapse;border-spacing: 0'><tr><td nowrap style='padding:7.5pt 7.5pt 7.5pt 7.5pt'><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif";text-transform:uppercase'><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=38&elqTrackId=3817e16204014ef6a819e1cdf12d4448&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><span style='color:white;text-decoration:none'>Slideshows</span></a> <o:p></o:p></span></p></td></tr></table></td><td style='padding:0cm 0cm 0cm 0cm'></td></tr></table></td></tr></table></div></td><td style='padding:0cm 0cm 0cm 0cm'></td></tr></table></div><p class=MsoNormal><o:p> </o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=600 style='width:450.0pt;background:white;border-collapse:collapse;border-spacing: 0'><tr><td style='padding:11.25pt 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=5 cellpadding=0 width=600 style='width:450.0pt;background:white'><tr><td style='padding:0cm 0cm 0cm 0cm'><p class=MsoNormal><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=363&elqTrackId=6b5d0c24f2bb413f97886fbf72713563&GUID=C49B511B-6B22-4FB4-B49E-BAAA68D63CCE&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1" target="_blank"><strong><span style='font-size:14.0pt;font-family:"Tahoma","sans-serif";color:#333333;text-decoration:none'>PROSTATE CANCER</span></strong></a> <o:p></o:p></p></td></tr></table></div></td></tr><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left width="100%" style='width:100.0%;border-collapse:collapse;border-spacing: 0' id=articles><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=362&elqTrackId=6b5d0c24f2bb413f97886fbf72713563&GUID=C49B511B-6B22-4FB4-B49E-BAAA68D63CCE&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><b><span style='font-size:14.0pt;font-family:"Tahoma","sans-serif";color:#056C9C'>Improved Pain, Fatigue With Abiraterone/Prednisone in Prostate Cancer</span></b></a> <o:p></o:p></p></td></tr><tr><td style='padding:3.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Tahoma","sans-serif";color:#333333'>Adding abiraterone plus prednisone to ADT improves patient-reported outcomes and quality of life in patients with metastatic castration-naive prostate cancer. <a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=362&elqTrackId=6b5d0c24f2bb413f97886fbf72713563&GUID=C49B511B-6B22-4FB4-B49E-BAAA68D63CCE&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><span style='color:#056C9C'> Read more </span></a> <o:p></o:p></span></p></td></tr><tr><td style='padding:18.75pt 3.75pt 3.75pt 3.75pt'><p class=MsoNormal><a href="http://app.network.modernmedicine.com/e/er?elq_mid=453&elq_cid=37808&s=727777198&lid=361&elqTrackId=6b5d0c24f2bb413f97886fbf72713563&GUID=C49B511B-6B22-4FB4-B49E-BAAA68D63CCE&elq=cb09b07d539c4158a03faab00dad24bb&elqaid=453&elqat=1"><b><span style='font-size:14.0pt;font-family:"Tahoma","sans-serif";color:#056C9C'>Variations in Prostate Cancer Outcome With Increasing TTR After ADT</span></b></a> <o:p></o:p></p></td></tr><tr><td style='padding:3.75pt 3.75pt 11.25pt 3.75pt'><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Tahoma","sans-serif";color:#333333'>The time to testosterone rebound was associated with differences in prostate cancer-specific and cardiovascular mortality among men who underwent RT and ADT. <a 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