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</o:shapelayout></xml><![endif]--></head><body bgcolor=whitesmoke lang=EN-CA link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Hi all:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>See below for the August <i>Hot SHEET</i> from Us TOO.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>You are encouraged to subscribe to it so you don’t have to rely on me remembering to forward it.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Thx.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Glen<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div><div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm'><p class=MsoNormal><b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span lang=EN-US style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> Us TOO International] <br><b>Sent:</b> August 1, 2019 10:43 AM<br><b>To:</b> glen46nor@gmail.com<br><b>Subject:</b> Hot SHEET August 2019<o:p></o:p></span></p></div></div><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td style='padding:0cm 0cm 0cm 0cm'><div><p class=MsoNormal align=center style='text-align:center;mso-line-height-alt:.75pt'><span style='font-size:1.0pt'><img id="_x0000_i1025" 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style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhTpcMUgoCGsriNvU-rJen8gEEyHNWhfq-LgZV8jbpFW0Ld288vyVfzTpTS7izjRtYoWue3Fd_1gS_k8lgYzHb58=&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><i><span style='font-size:9.0pt;color:black'>Bayer</span></i></a></span><i><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'>, </span></i><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhctsuuf1CQ6ay411i_-7fXIDY4idljyhIImpbKbs2JyRdis4fLkxdsw_O2YAA2hyVJrNekwHEVLoDemo2HUD8ANC7EWAmNd9bQ==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><i><span style='font-size:9.0pt;color:black'>Astellas</span></i></a></span><i><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'> / </span></i><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhQrT-C_kOozqn5KhWoy009wuUcA8g1HoNQC4VMfh5IftPz3bDzXidXDlkCKJsZbOEqSwiuKSvIBXzMAOMf-Hm2nPhAXyIR-FcA==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><i><span style='font-size:9.0pt;color:black'>Pfizer</span></i></a></span><i><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'>.</span></i><i><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:#0C1D32'> </span></i><i><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:#141414'>Thank You!</span></i><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><i><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:#0078C1'>Navigation Tip: Click on blue text that’s underlined and in bold for link to more information.</span></i><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span class=greeting-tag><span style='font-family:"Arial","sans-serif";color:black'>Hello Glen,</span></span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Arial","sans-serif";color:black'>We hope that the</span><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhSg3f6AgWhr23wr3QlBl5tO8gTu04mJlSR7eNYxKFpfdMYcHIvV67DslCCR0H1mzcN5nb6etzXiD1L6DAJcFUs2I96kQJQvSXhHjJqNhcZLHLoJmojJuLbmWoIEHKJBSRLbZ8Bzrkrg5lRGf4l6Jb5CvgBBMubT1Tg==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>August 2019 Hot SHEET</span></b></a></span><b><span style='font-family:"Arial","sans-serif";color:#0070C0'> newsletter</span></b><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-family:"Arial","sans-serif";color:black'>finds you doing well and enjoying the summer season! In addition to the newsletter, we hope that the following updates and information are of interest to you.</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><b><span style='font-family:"Arial","sans-serif";color:#0070C0'>Men with metastatic castration-resistant prostate cancer</span></b><b><span style='font-family:"Arial","sans-serif";color:#333333'> </span></b><span style='font-family:"Arial","sans-serif";color:black'>are invited to consider enrollment in one of two international, Pfizer-sponsored studies of talazoparib, a PARP inhibitor.</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><p class=MsoNormal style='margin-left:30.0pt;text-indent:-12.0pt;mso-list:l0 level1 lfo1'><![if !supportLists]><span style='font-size:10.0pt;font-family:Symbol;color:#333333'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span style='font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhQUmZ7_3CPJPORLj5foBKGXGU9iti2V-_n93bDbzuuYDC9j0ET1h8BtfQ__dkqVDtWoTBRvWRRS6sH4UQWP9pYD2tBbH8dH3yumtuUMItCfxuecDP7lYv8o12A9HFPVNUXIGsBPB5SOk40x9ZmJiN9VL3MNbzVsV8X5J1k2ux65H&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='color:#006DB0'>TALAPRO-1</span></b></a></span><b><span style='font-family:"Arial","sans-serif";color:black'>:</span></b><span style='font-family:"Arial","sans-serif";color:black'> A phase 2, open-label study of talazoparib in men with DNA damage repair (DDR)-deficient metastatic castration-resistant prostate cancer (mCRPC) who previously received taxane-based chemotherapy and progressed on at least 1 novel hormonal therapy (NHT). </span><span style='font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p><p class=MsoNormal style='margin-left:30.0pt;text-indent:-12.0pt;mso-list:l0 level1 lfo1'><![if !supportLists]><span style='font-size:10.0pt;font-family:Symbol;color:#333333'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span style='font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhQUmZ7_3CPJPgDCHrGPtCNNU57yEyv5210I8-_W2PA6o3J3ySv5DoX8VGymnXjqJnYQui59dO6OaRKx5ifr7mXCz6ckV_nXEDCDdJElIsGobdLsggZAOA_7PjmL3TfyvQGm4nXzydUygIb0AZZGLafkt2pjsPddrUN3u8ZxQeAwM&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='color:#0078C1'>TALAPRO-2</span></b></a><b>:</b> </span><span style='font-family:"Arial","sans-serif";color:black'>A phase 3, randomized, double-blind, placebo-controlled study of talazoparib with enzalutamide in metastatic castration-resistant prostate cancer (mCRPC).</span><span style='font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p><p class=MsoNormal style='margin-left:30.0pt;text-indent:-12.0pt;mso-list:l0 level1 lfo1'><![if !supportLists]><span style='font-size:10.0pt;font-family:Symbol;color:#333333'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span style='font-family:"Arial","sans-serif";color:black'>For an overview of these studies in patient-friendly language <b>visit:</b> </span><span style='font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhQyc_OoowkdnqfTLBUSnkbBxTY0X0rXr4t_ta1t4Ow9SRpXZc9S2bwkYRevgCoFpwc757W-n6uG-phVPtK9SzaGh974i7YhCgHYzuClSg5uC&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><i><span style='color:#006DB0'>www.talaprotrials.com/Public</span></i></b></a></span><span style='font-family:"Arial","sans-serif";color:black'>. </span><span style='font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhcSE-CdnCGVf0GGnjlJgNIgnW40npMfv3YjiHOxlLhAl9AbqUXxUTsqaa_JQPEgejgXpHPP-6aKQT9rBuNU_n4e1aDJZEg_0RA==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>IRONMAN</span></b></a></span><b><span style='font-family:"Arial","sans-serif";color:#333333'> </span></b><b><span style='font-family:"Arial","sans-serif";color:#0070C0'>is a registry recruiting 5,000 men with advanced prostate cancer from 9 countries.</span></b><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-family:"Arial","sans-serif";color:black'>More than 366,000 men die of prostate cancer globally every year. Research on a man's type of prostate cancer, treatment and side effects will help inform what causes prostate cancer, how to stop or slow its progression, and how to provide the best care to enable men to live the best quality life possible. </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhWQa-Njhz6c1c41umPWraELRPYRXV1lG2DIhQ-dWzVdrTeieR-rdA8QSocRsSJORALG_umS42cMIQclCBrOO6q-ZEvQBR1zk0g==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>The Metastatic Prostate Cancer Project</span></b></a></span><b><span style='font-family:"Arial","sans-serif";color:#0070C0'> is a nationwide genomic research study</span></b><span style='font-family:"Arial","sans-serif";color:#36120D'> </span><span style='font-family:"Arial","sans-serif";color:black'>for men with metastatic and/or advanced prostate cancer. Patients can join online and participate by sharing their medical information and samples. The project’s goal is to release new data to help researchers better understand metastatic and advanced prostate cancer, and accelerate discoveries.</span><span style='font-family:"Arial","sans-serif";color:#36120D'> </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><b><i><span style='font-family:"Arial","sans-serif";color:#0070C0'>BRCA</span></i></b><b><span style='font-family:"Arial","sans-serif";color:#0070C0'> Blue</span></b><span style='font-family:"Arial","sans-serif";color:black'> is a program to help educate patients and caregivers about the </span><b><span style='font-family:"Arial","sans-serif";color:#0070C0'>connection between <i>BRCA </i>gene mutations and prostate cancer</span></b><span style='font-family:"Arial","sans-serif";color:black'>. While some people may have heard about BRCA genes and their relationship to breast and ovarian cancers, research has shown a connection to other cancers as well – including prostate cancer. In fact, men who have a <i>BRCA </i>mutation are at a higher risk for developing prostate cancer than men without a <i>BRCA </i>mutation. </span><b><span style='font-family:"Arial","sans-serif";color:#0070C0'>To learn more about this important gene, please visit </span></b><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhSg3f6AgWhr2LABIzlfyx8wXrp2EpKPGfKrrJnkmN2nPG36B2NWQt0gjPee4W8Y2cpW4Du3hCGe3opU7gZ4ou0auBh5pIL0R_A==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>BRCAblue.com</span></b></a></span><b><span style='font-family:"Arial","sans-serif";color:#0070C0'>.</span></b><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Arial","sans-serif";color:black'>We’re looking forward to hosting the</span><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhfp28EpUfmYTyaYmq8qvciwNaVP4HYtyMqiDc2s6vugxWg2KBAPLQ8EaEoe-nL5uXF_rSxyF20ktzQ7_fj4q2_m55Nt7tct8IxqgXteupgVJjWOrDU-pHGY=&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>15</span></b></a><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhfp28EpUfmYTyaYmq8qvciwNaVP4HYtyMqiDc2s6vugxWg2KBAPLQ8EaEoe-nL5uXF_rSxyF20ktzQ7_fj4q2_m55Nt7tct8IxqgXteupgVJjWOrDU-pHGY=&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><sup><span style='font-size:10.0pt;color:#0070C0;position:relative;top:-3.0pt;mso-text-raise:3.0pt'>th</span></sup></b></a><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhfp28EpUfmYTyaYmq8qvciwNaVP4HYtyMqiDc2s6vugxWg2KBAPLQ8EaEoe-nL5uXF_rSxyF20ktzQ7_fj4q2_m55Nt7tct8IxqgXteupgVJjWOrDU-pHGY=&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'> Annual SEA Blue Chicago Prostate Cancer Walk & Run</span></b></a></span><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-family:"Arial","sans-serif";color:black'>on Sunday, September 15, in Lincoln Park! </span><b><span style='font-family:"Arial","sans-serif";color:#005487'>SEA</span></b><span style='font-family:"Arial","sans-serif";color:black'> is an acronym for </span><b><span style='font-family:"Arial","sans-serif";color:#005487'>S</span></b><span style='font-family:"Arial","sans-serif";color:black'>upport, </span><b><span style='font-family:"Arial","sans-serif";color:#005487'>E</span></b><span style='font-family:"Arial","sans-serif";color:black'>ducate and </span><b><span style='font-family:"Arial","sans-serif";color:#005487'>A</span></b><span style='font-family:"Arial","sans-serif";color:black'>dvocate; and </span><b><span style='font-family:"Arial","sans-serif";color:#005487'>blue is to prostate cancer</span></b><span style='font-family:"Arial","sans-serif";color:black'> as pink is to breast cancer. Register to join us at the event, if possible; or register as a virtual mover at no charge if you will not attend in person and want to help fundraise. For a glimpse into what makes this event so special for so many people, </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhfp28EpUfmYTRa_Eu6R7m86ju4XST9GjUb4CYvhnbQ8eCry6NqybBWLdaOHS5IIQa1ImrIHqtpPCg5vafkblOCG8FnvULfhaNweaBo-6EuF6XGoDjUS8lQ5XUwg-jkunTFZ0LossGH5hFmBHHABe1ME=&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>check out the video</span></b></a></span><b><i><span style='font-family:"Arial","sans-serif";color:black'>. </span></i></b><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Arial","sans-serif";color:black'>Join PCRI from September 6-8 for the</span><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhedW2EIavK7mdAbRiVaUmYvYjs7RtWHJknBxNct16RNkJ3-lZYcFttPz75dNFZ-tJ_uhMQCu65ZbULaAA3iCbmsj9RTvRDCcZTBaWUscqNne&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>2019 PCRI Prostate Cancer Patient Conference</span></b></a></span><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-family:"Arial","sans-serif";color:black'>and get face to face with prostate cancer experts in every field. Hosted at the Los Angeles Airport Marriott, the PCRI conference is a full-featured educational experience for prostate cancer patients and caregivers. Each day consists of straightforward presentations, extended Q+A sessions, individualized small-group sessions, and a variety of fun and enriching activities to facilitate camaraderie. You can expect to gain a comprehensive knowledge of your disease and become empowered to make the best decisions for your life. Choose your strategy and win the fight! </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhSg3f6AgWhr2R3EtNQO4T0UN5vz6AXeb8_r4MqgPuTc3pZMaIYL-b62ts6080aBc4bEqQ9WyJFyo8KT5CVnXDVuZEedJlq67zA==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>Watch the new promotional video!</span></b></a></span><span style='font-family:"Arial","sans-serif";color:#333333'> </span><span style='font-family:"Arial","sans-serif";color:black'>Register using the code "ustoo" for a discounted patient registration rate of $30.00.</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Arial","sans-serif";color:black'>And be sure to check out </span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhedW2EIavK7mGvc_cft_NiylzCou-XLtxG6BGRllOKIjI7-QlufsktX0dPlsGAgJ1j2Z5t1RcQrkBFlFscUHGVJrwpg10-SjH_CcCryiwnxXIzvdeoT9T6jPaSo0DQYx4w==&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ==" target="_blank"><b><span style='font-size:12.0pt;color:#0070C0'>educational video from the 2019 CPCC/UCSF Patient Conference on Prostate Cancer</span></b></a></span><span style='font-family:"Arial","sans-serif";color:#333333'>. </span><span style='font-family:"Arial","sans-serif";color:black'>The event took place on June 8 and was presented by the California Prostate Cancer Coalition and UCSF Helen Diller Family Comprehensive Cancer Center.</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'> <o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Arial","sans-serif";color:black'>Take care and let us know how we can help you with educational resources, support services and personal connections to others in the prostate cancer community.</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Arial","sans-serif";color:black'></span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Arial","sans-serif";color:black'>All the best,</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div></div></div></td></tr></table></div></td></tr></table></div><p class=MsoNormal align=center style='text-align:center'><o:p> </o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td width="100%" valign=top style='width:100.0%;padding:0cm 0cm 0cm 0cm;word-wrap: break-word'><div><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;word-wrap: break-word'><tr><td valign=top style='padding:7.5pt 15.0pt 7.5pt 15.0pt'><div><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 align=left style='border-collapse:collapse;margin-right:3.5pt'><tr style='height:.75pt'><td valign=top style='padding:0cm 0cm 0cm 0cm;height:.75pt'><div><p class=MsoNormal align=center style='text-align:center'><img border=0 width=219 id="_x0000_i1032" src="https://files.constantcontact.com/5f7db5e8601/7912781c-c841-4f8c-badc-92d406ea6a5b.jpg"><o:p></o:p></p></div></td><td width=15 valign=top style='width:11.25pt;padding:0cm 0cm 0cm 0cm;height:.75pt'><p class=MsoNormal align=center style='text-align:center;mso-line-height-alt:.75pt'><img border=0 width=15 height=1 id="_x0000_i1033" src="https://imgssl.constantcontact.com/letters/images/sys/S.gif"><o:p></o:p></p></td></tr><tr style='height:.75pt'><td valign=top style='padding:0cm 0cm 0cm 0cm;height:.75pt'><p class=MsoNormal align=center style='text-align:center;mso-line-height-alt:3.75pt'><img border=0 width=1 height=5 id="_x0000_i1034" src="https://imgssl.constantcontact.com/letters/images/sys/S.gif"><o:p></o:p></p></td><td width=5 valign=top style='width:3.75pt;padding:0cm 0cm 0cm 0cm;height:.75pt'><p class=MsoNormal align=center style='text-align:center;mso-line-height-alt:.75pt'><img border=0 width=5 height=1 id="_x0000_i1035" src="https://imgssl.constantcontact.com/letters/images/sys/S.gif"><o:p></o:p></p></td></tr></table></div><div><div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'>Chuck Strand, Chief Executive Officer</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'>James Hutson, Development Director</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'>Jackie Konieczka, Office Manager</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'>Terri Likowski, Program Director - Support Group Services</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Arial","sans-serif";color:black'>Tim Mix, Communications Manager</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div></div></div></td></tr></table></div></td></tr></table></div><p class=MsoNormal align=center style='text-align:center'><o:p> </o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td width="100%" valign=top style='width:100.0%;padding:0cm 0cm 0cm 0cm'><div><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td valign=top style='padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%;cursor:default'><tr><td width="100%" valign=top style='width:100.0%;padding:6.75pt 0cm 6.75pt 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="93%" style='width:93.0%;border-collapse:collapse;min-width: 93%'><tr style='height:.75pt'><td style='background:black;padding:0cm 0cm 0cm 0cm;height:.75pt'><div><p class=MsoNormal align=center style='text-align:center;mso-line-height-alt:.75pt'><img border=0 width=5 height=1 id="_x0000_i1036" src="https://imgssl.constantcontact.com/letters/images/sys/S.gif"><o:p></o:p></p></div></td></tr></table></div></td></tr></table></div></td></tr></table></div></td></tr></table></div><p class=MsoNormal align=center style='text-align:center'><o:p> </o:p></p><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;min-width: 100%'><tr><td width="100%" valign=top style='width:100.0%;background:white;padding:0cm 0cm 0cm 0cm;word-wrap: break-word'><div><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse;word-wrap: break-word'><tr><td valign=top style='padding:7.5pt 15.0pt 7.5pt 15.0pt'><div><div><div><p class=MsoNormal align=center style='text-align:center'><span style='font-size:7.5pt;font-family:"Arial","sans-serif";color:#333333'>Connect with Us TOO on Social Media:</span><span style='font-size:10.5pt;font-family:"Arial","sans-serif";color:#333333'><o:p></o:p></span></p></div></div></div></td></tr></table></div><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td style='padding:0cm 15.0pt 7.5pt 15.0pt'><div><p class=MsoNormal align=center style='text-align:center'><a href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhTpcMUgoCGsrs4zG9tucBvDQcRgMLIDmrGzhtSKNsGFzdp1NlOdBwCJAae2Cv9BYfCBA1F-bFyj4Xax82Ne6TLzlk-31Ulz-5vzUL7fqcgSKfa9CJI3vCVY=&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ=="><span style='text-decoration:none'><img border=0 width=32 id="_x0000_i1037" 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href="http://r20.rs6.net/tn.jsp?f=001RQ2WyiyWwcmMsBSuI5oKaRkOeh3ykTlQIh7LCXE-L5IOafTDD3xwhaxxnnlOF5A94WGxDr2npYrPYS7uyIIN0MWlYIt_lbHCdPEXlmHro6qaoxaP9W64La86u9IHB8QFeAZqalc_Hiahhct-inHY9qKWFU43uSxO8YZ3Gl2OTxY=&c=j5xyfOwgiIRhC7FBYXKq54xMoEMjLEZZ8KNsQ1F8A7NkMmWOB6h0BQ==&ch=as6f8D7f17uUXIn940rA1d7CdRXeQVuYqMJq1IVpANgU_G_BPkWDuQ=="><span style='text-decoration:none'><img border=0 width=32 id="_x0000_i1039" src="https://imgssl.constantcontact.com/galileo/images/templates/Galileo-SocialMedia/linkedin-visit-default.png" alt=LinkedIn> </span></a><o:p></o:p></p></div></td></tr></table></td></tr></table></div></div></td></tr></table></div></td></tr></table></div></td></tr></table></div></td></tr></table></div></div></td></tr><tr><td style='padding:0cm 0cm 0cm 0cm'></td></tr></table><p class=MsoNormal><o:p> </o:p></p><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;background:white;border-collapse:collapse'><tr><td width="100%" valign=top style='width:100.0%;padding:0cm 0cm 0cm 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width="100%" style='width:100.0%;border-collapse:collapse'><tr><td valign=top style='padding:12.0pt 0cm 12.0pt 0cm'><div align=center><table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=580 style='width:435.0pt;border-collapse:collapse'><tr><td valign=top style='padding:3.0pt 0cm 3.0pt 0cm'><p class=MsoNormal align=center style='text-align:center'><span class=footer-column><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";color:#5D5D5D'>Us TOO International</span></span><span class=footer-mobile-hidden><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";color:#5D5D5D'> | </span></span><span class=footer-column><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";color:#5D5D5D'>2720 S. 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