[CTN] CTN seminar: Dr. Mriganka Sur, 3:30 Sept 22, PAS 2464

[Bryan Tripp]

Hi everyone,

This is just a reminder about the seminar tomorrow (Tuesday), where your
questions about cortical inhibition (subtraction? division? why are the
inhibitory neurons so diverse?) may finally be answered.

Bryan


On Tue, Sep 15, 2015 at 5:20 PM, Bryan Tripp <bptripp at gmail.com> wrote:

> Hi everyone,
>
> Dr. Mriganka Sur (MIT) will give the next seminar, Tuesday of next week.
> The title and abstract follow.
>
> The time and place are as usual, 3:30 in PAS 2464.
>
> Please let me know if you would like to meet Professor Sur individually
> and/or join us for dinner after the talk.
>
> Hope to see you there,
>
> Bryan
>
>
>
> The Functional Logic of Cortical Circuits
>
> Cortical circuits transform simpler inputs into complex outputs that
> underlie behavior and cognition. Neuronal circuits of the cortex involve
> feedforward and top-down inputs, connections between specific types of
> excitatory and inhibitory neurons, and neuromodulatory inputs to specific
> cell classes. We have utilized novel experimental approaches – including
> two-photon imaging of neurons across multiple cortical regions in behaving
> mice, targeted recordings from specific neuron types, and activation and
> suppression of neuron classes - to analyze circuits that mediate visual
> perception and behavior. I will describe some recent results demonstrating
> powerful circuit motifs underlying spatial and temporal processing in the
> cortex. These include inhibitory computations performed via two fundamental
> operations, division and subtraction, by  parvalbumin (PV) and somatostatin
> (SOM) expressing neurons; modulation of temporal processing by
> acetylcholine via a unique inhibitory-disinhibitory microcircuit; and
> information flow and attractor dynamics in neuronal populations of the
> frontal cortex during memory-guided behavior.
>
> Wilson, N.R., C.A. Runyan, F.L. Wang, and M. Sur. Division and subtraction
> by distinct cortical inhibitory networks in vivo. Nature 488: 343-348, 2012.
> El-Boustani, S. and M. Sur. Response-dependent dynamics of cell-specific
> inhibition in cortical networks in vivo. Nature Communications [doi:
> 10.1038/ncomm6689], 2014.
> Chen N, H. Sugihara and M. Sur. An acetylcholine-activated microcircuit
> drives temporal dynamics of cortical activity. Nature Neuroscience 18:
> 892-902, 2015.
>
>
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