[CTN] CTN seminar: Steve Prescott (University of Toronto) 3:30 January 23, PAS 2464

[Bryan Tripp]

Hi everyone,

Please join us for the first CTN talk of 2018. Steve Prescott will join us
from the University of Toronto. The title and abstract follow. Hope to see
you there!

Bryan


Somatosensory coding gone wrong: The origins of neuropathic pain

Pain is the normal sensory response to noxious stimulation. But
pathological changes in neural coding can result in innocuous somatosensory
input being misperceived as painful. This so-called neuropathic pain is
notoriously difficult to treat and is, therefore, a significant clinical
problem. In my presentation, I will discuss our ongoing work to uncover the
cellular and circuit properties that control how somatosensory information
is normally processed, and how pathological changes in those properties
contribute to neuropathic pain. The identification that certain
pathological states are degenerate (i.e. can be produced via distinct
molecular changes) may help explain why neuropathic pain is so difficult to
treat.
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