[CTN] CTN Seminar October 29 - Jiannis Taxidis (U of T)

Sue Ann Campbell sacampbell at uwaterloo.ca
Mon Oct 21 09:11:12 EDT 2024


Hello Everyone,

I hope that you enjoyed Reading Week.

Our next CTN speaker is in just over a week:

Tuesday, October 29, 3:30 p.m., DC 1304

The speaker is Jiannis Taxidis from U of T https://physiology.utoronto.ca/faculty/jiannis-taxidis
His title and abstract are below.

Hope to see you there.

Regards,

Sue Ann

Title: Remembering what happened when: Dynamics of hippocampal sequences linking memories across time

Abstract:

How does the brain keep track of events we need to remember as well as the intervals between them? This process involves the hippocampus. When a series of sensory cues, separated by time gaps, is experienced by mice, hippocampal spiking sequences encode these cues and link them in memory by tiling the time gaps between them. These sequences form activity trajectories across ‘memory space’, retaining information on the identity of the most recent cue and the time elapsed since its presentation. But the population dynamics underlying the emergence, stability and reactivation of such memory-encoding sequences remain unclear. I will explore this topic by presenting longitudinal 2-photon calcium imaging and 1-photon voltage imaging of cell-type-specific activity while mice perform a memory task. I will also describe computational modeling work on sequence reactivation. Collectively this work will shed light on how the hippocampus uses an optimal strategy for encoding and linking information in memory.



_______________________________________________


Dr. Sue Ann Campbell (she/her)

Professor and University Research Chair

Department of Applied Mathematics & Centre for Theoretical Neuroscience<https://uwaterloo.ca/centre-for-theoretical-neuroscience/>

Associate Dean, Research, Faculty of Mathematics

University of Waterloo

Waterloo ON N2L 3G1

https://www.math.uwaterloo.ca/~sacampbe/

President, Canadian Applied and Industrial Mathematics Society<https://caims.ca/>


I acknowledge that I live and work on the traditional territory of the Chonnonton, Anishinaabeg and Haudenosaunee peoples. The University of Waterloo main campus is located on the Haldimand tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is co-ordinated within the Office of Indigenous Relations.

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