[Hopespringpcsg] FW: Update on PSA Screening: Benefits and Risks

Thu Mar 12 07:37:39 EDT 2015

Hi all:

See below wrt PSA screening.

Take care,

Glen

From: Scientific American Health After 50 Alerts [mailto:ScientificAmericanHealthAfter50 at sp.healthafter50.com] 
Sent: March 12, 2015 6:03 AM

Subject: Update on PSA Screening: Benefits and Risks

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Benefits and Risks

The value of prostate-specific antigen (PSA) screening for prostate cancer is the subject of much debate today. Results from a large long-term European study provide important insight. The study was published online in Lancet (August 6, 2014).

More than 160,000 men between the ages 55 and 69 years from eight countries were enrolled. About 73,000 of the men were randomly chosen to undergo screening with a PSA test every four years (except in Sweden, where men were screened every other year). The remaining study participants weren't offered PSA screening.

Over 13 years, men who were offered PSA screening had a 21 percent lower risk of dying of prostate cancer than their counterparts who weren't offered screening. Stated another way, PSA screening prevented one death for every 27 cases of prostate cancer it detected.

Take-away message. These findings provide confirmation that prostate cancer-related deaths are lower in men who are screened. But it's important to keep in mind that overdiagnosis occurs in roughly 40 percent of cases detected by screening.

In spite of these results, there is no one-size-fits-all screening strategy. All men and their doctors should weigh the benefits and risks of screening based on the man's individual circumstances and preferences.

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