[Hopespringpcsg] FW: ASCO: 18 Month ADT Enough in High-Risk Prostate Cancer?
Glen Tolhurst
glen46nor at gmail.com
Wed Jun 7 20:04:45 EDT 2017
Hi all:
Below are several interesting articles relating to PCa.
Thx.
Glen
From: Cancer Network [mailto:cancernetwork at email.cmpmedica-usa.com]
Subject: ASCO: 18 Month ADT Enough in High-Risk Prostate Cancer?
Plus: Does ERG expression predict docetaxel benefit in prostate cancer?
To view this email as a web page, click
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137b774511cf65baf10257174b6c3edad2faf41228340535578523abb9137954b9d2e65b9fd9
507c75d13708c87045757ea4aea27980f> here.
Modern Medicine Network
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90016d08194cad3da8faf554b2d8c90e4e22a3d9308ac10743cc447ff6f313> Cancer
Network
ASCO 2017 | June 7, 2017
<http://click.email.cmpmedica-usa.com/?qs=3c25bc924da5c8a27f94e5e1a582152917
9b4cb147bdfd8e2f0ee0e6420557ab0fb4a966688010394568db50f2ad3389> Prostate
Cancer Highlights From ASCO 2017
Cancer Network presents exclusive coverage on prostate cancer from the 2017
American Society of Clinical Oncology (ASCO) Annual Meeting, held June 2-6.
We bring you expert interviews and reports on the latest trials and
scientific advances that are changing the way this malignancy is managed and
treated.
<http://click.email.cmpmedica-usa.com/?qs=3c25bc924da5c8a25cfd3c224af225d259
d7ebf68686ce63a7ec0465b6f888e205d3cd4e094d9f65fb054bbb0da5ecd4> Reducing ADT
to 18 Months May Be Sufficient in High-Risk Prostate Cancer
Androgen deprivation therapy can be safely reduced from 36 months to 18
months in high-risk prostate cancer, according to results of a phase III
trial.
<http://click.email.cmpmedica-usa.com/?qs=3c25bc924da5c8a25cfd3c224af225d259
d7ebf68686ce63a7ec0465b6f888e205d3cd4e094d9f65fb054bbb0da5ecd4> Read more
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ff03f317e39ae4d739cea04758ef43d2620c6b28b7738370c976c136c4d83b> Does ERG
Expression Predict Docetaxel Benefit in Prostate Cancer?
Tumor expression of the oncogene ERG might predict patient benefit from
adding docetaxel to androgen deprivation therapy, according to analyses of
two phase III clinical trials.
<http://click.email.cmpmedica-usa.com/?qs=3c25bc924da5c8a2c747cef284d734a33c
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05797f61e2c6285c3d4ab528f866f2120f07ecfa09801a785e37fca326bb31> Signature
for Aggressive-Variant CRPC Predicts Platinum Sensitivity
A molecular signature for aggressive-variant prostate carcinoma can predict
which men with castrate-resistant prostate cancer will benefit from
cabazitaxel with or without carboplatin.
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Post-Progression Enzalutamide/Abiraterone Not Effective in Metastatic CRPC
Continued enzalutamide with abiraterone failed to improve PFS in men with
metastatic castration-resistant prostate cancer who progressed on
enzalutamide alone.
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IN CASE YOU MISSED IT
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Abiraterone/ADT Combo Increased Prostate Cancer Survival
image description here
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Combined therapy with abiraterone acetate/prednisone plus ADT significantly
improved overall survival and radiographic progression-free survival among
men with metastatic hormone-naive prostate cancer.
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Abiraterone Slowed Progression of Advanced Prostate Cancer
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Abiraterone at the start of ADT for men with metastatic prostate cancer
significantly improved overall survival and failure-free survival, with
manageable toxicity.
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