[Hopespringpcsg] FW: [PPML] More High-Risk Prostate Cancer Now in the US Than Before

[Glen Tolhurst]

Hi all:
Interesting article on screening for PCa.
Thx.
Glen


Subject: [PPML] More High-Risk Prostate Cancer Now in the US Than Before

https://www.medscape.com/viewarticle/894477

" As predicted <https://www.medscape.com/viewarticle/878438> by urologists in 2012 after the recommendations were released, there has been a consistent, stepwise increase in cancers of higher Gleason score, as well as a stepwise increase in the median level of prostatic-specific antigen (PSA), in the 4 years after the USPSTF recommendations were released compared to the 4 years before the recommendations were issued...."

"As previously reported <https://www.medscape.com/viewarticle/885186>, a new analysis of data from the European Randomized Study of Screening for Prostate Cancer (ERSPC) and the PLCO trial now indicates that both studies support a prostate-cancer mortality benefit with PSA screening.

The new analysis showed a 25% to 31% lower risk for prostate cancer mortality in the ERSPC and a 27% to 32% lower risk in the PLCO among men who were screened compared to men who were not screened."


Reference: European Association of Urology (EAU) 2018 Congress. Abstracts
268 and 269, presented March 17, 2018.

PLCO =  Prostate, Lung, Colorectal, and Ovarian Cancer Screening