[CTN] CTN Seminar: Aimee Nelson (McMaster), 3:30 March 6, PAS 2464.

[Bryan Tripp]

Hi everyone,

Just a reminder about the talk tomorrow.

Bryan


On Thu, Mar 1, 2018 at 12:14 AM, Bryan Tripp <bptripp at gmail.com> wrote:

> Hi everyone,
>
> Next Tuesday we will have a talk by Professor Aimee Nelson from McMaster.
> The title and abstract follow.
>
> Bryan
>
>
> Changes in the organization of the motor cortex that follow incomplete
> spinal cord injury
> Movement training for improving upper limb control is an essential
> component of rehabilitation for individuals with spinal cord injury (SCI).
> Understanding the cortical representation of arm muscles in SCI is
> fundamental to designing more effective movement training regimes.  In
> uninjured individuals, the primary motor cortex (M1) contains overlapping
> muscle representations, an organization that reflects muscle synergies.
> This organizational feature has yet to be studied in SCI yet is
> considered a key element that defines the coordinated action of multiple
> muscles during human movement. Using Transcranial magnetic stimulation
> (TMS), we investigated the bilateral representation and overlapping
> distribution of muscles of the upper limb in chronic cervical SCI and
> aged-matched controls (n=9, each group). Muscles studied included the
> abductor pollicus brevis (APB), flexor carpi radialis (FCR) and biceps
> brachii (BB) and the cortical territory (cm2), overlapping territory (cm2)
> of the target muscles, and center of gravity were computed. Results
> indicate a reduction in the cortical territory dedicated to all three
> muscles in SCI (i.e. reduced complete overlap) compared to uninjured
> controls.  Further, SCI had greater cortical territory dedicated to a
> single or dual muscle representation. These data indicate that overlapping
> organization is preserved in the motor cortex of SCI, however, the
> overlapping representation does not extend to all three muscles. The
> implication from these data is that movement training emphasizing synergies
> that incorporate all three muscles (APB, FCR, BB) may promote greater
> representational overlap (similar to uninjured controls) and provide
> functional gains in motor control.
>
>
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