[CTN] CTN seminar: Matt van der Meer (Dartmouth College) April 9, 3:30 in PAS 2464

[Bryan Tripp]

Hi everyone,

We have a special seminar shortly after Brain Day this year, by Matt van
der Meer from Dartmouth College. Many of you will know Matt from his time
here at the University of Waterloo, as a professor in the Department of
Biology, and coincidentally, past organizer of the CTN Seminar Series.

Bryan

"Oscillations as an organizing principle for understanding information
processing in the rodent ventral striatum"

The ventral striatum (vStr) is a central node in brain circuits that
contribute to motivated behavior, and its dysfunction is consistently
implicated in the etiology of substance use disorders. Despite major
research efforts focused on this brain structure, it has proven difficult
to synthesize its structure, dynamics and function into a coherent theory.
I will present data from rodents suggesting that oscillations in vStr
activity provide an organizing principle, albeit one full of pitfalls, to
address this issue. These oscillations highlight the dynamic nature of
interactions with input structures such as the prefrontal and orbitofrontal
cortex, and the surprising role of the piriform cortex in coordinating
these interactions. Beyond providing new insights into vStr function, these
results also provide a striking example of the complex relationships
between spiking activity and local field potentials.
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